Consider the following statements:
(A) Coenzyme or metal ion that is tightly bound to
enzyme protein is called prosthetic group.
(B) A complete catalytic active enzyme with its
bound prosthetic group is called apoenzyme.
Select the correct option.
AI-generated explanation. Check against your textbook.
Explanation:
According to NCERT, a prosthetic group is a non-protein component (like a coenzyme or a metal ion) that is tightly bound to the enzyme. Hence statement (A) is true. An apoenzyme is the protein part without its cofactor; the complete catalytic active enzyme with its bound prosthetic group is called a holoenzyme, not an apoenzyme. Therefore statement (B) is false. The correct option is 2: (A) true and (B) false.
🧠 Did You Know?
Prosthetic groups remain permanently attached to the enzyme, whereas some cofactors (like coenzymes) may associate and dissociate during catalysis, though in many cases they are tightly bound as part of the holoenzyme.
💡 NCERT Memory Line:
Prosthetic group = tightly bound non-protein part; Apoenzyme = protein part without cofactor; Holoenzyme = apoenzyme + prosthetic group.