If an inheritable mutation is observed in a population at high frequency, it is referred to as DNA _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• Fingerprinting
• Polymorphism
• Sequencing
• Cloning
Correct Option: B  [ Polymorphism ]

Remark: High frequency inheritable mutation constitutes polymorphism.

The probability of such variation is higher in _______ DNA sequences.

[Molecular-Basis-of-Inheritance] [class-xii ]

• Coding
• Non-coding
• Exon
• Promoter
Correct Option: B  [ Non-coding ]

Remark: Non-coding sequences accumulate mutations faster as they are less selected against.

DNA fingerprinting is the basis of _______ testing.

[Molecular-Basis-of-Inheritance] [class-xii ]

• Maternity
• Paternity
• Intelligence
• Blood
Correct Option: B  [ Paternity ]

Remark: It is used to settle paternity disputes.

The bulk DNA forms a _______ peak and the other small peaks are referred to as satellite DNA.

[Molecular-Basis-of-Inheritance] [class-xii ]

• Minor
• Major
• Satellite
• Small
Correct Option: B  [ Major ]

Remark: Bulk DNA forms a major peak in density gradient centrifugation.

A DNA sequence having the sequence 5'-GAATTC-3' is recognized by the restriction enzyme _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• BamHI
• EcoRI
• HindIII
• SalI
Correct Option: B  [ EcoRI ]

Remark: GAATTC is the recognition site for EcoRI.

Retroviruses have _______ genome.

[Molecular-Basis-of-Inheritance] [class-xii ]

• DNA
• RNA
• Protein
• Hybrid
Correct Option: B  [ RNA ]

Remark: Retroviruses have an RNA genome.

In a nucleosome, the histones are organized into an _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• Tetramer
• Hexamer
• Octamer
• Decamer
Correct Option: C  [ Octamer ]

Remark: Histones form an octamer core.

The typical distance between two base pairs is _______ nm.

[Molecular-Basis-of-Inheritance] [class-xii ]

• 0.34
• 3.4
• 20
• 2
Correct Option: A  [ 0.34 ]

Remark: 0.34 nm or 3.4 Angstroms.

The flow of information from DNA to RNA to Protein is called _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• Central Dogma
• Replication
• Transformation
• Transduction
Correct Option: A  [ Central Dogma ]

Remark: Crick termed this flow the Central Dogma.

Histones are positively charged because they are rich in _______ amino acids.

[Molecular-Basis-of-Inheritance] [class-xii ]

• Acidic
• Basic
• Neutral
• Aromatic
Correct Option: B  [ Basic ]

Remark: Basic amino acids (Lys, Arg) give histones a positive charge.