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Molecular Basis of Inheritance MCQs
Class XII Biology
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NCERT Based
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668 questions in this chapter
Question 571 of 668
📘 CLASS XII
How many base pairs are approximately present in the human haploid genome?
The human genome contains approximately 3.1647 billion base pairs, which is roughly 3 x 10^9 bp.
Question 572 of 668
📘 CLASS XII
Which human chromosome has the highest number of genes?
Chromosome 1 contains the most genes (2968), and Chromosome Y has the fewest (231).
Question 573 of 668
📘 CLASS XII
The methodology of sequencing only the coding parts of the genome is called?
ESTs involves identifying and sequencing only those genes that are expressed as RNA.
Question 574 of 668
📘 CLASS XII
The vectors used for cloning large DNA fragments in HGP were?
Bacterial Artificial Chromosomes (BAC) and Yeast Artificial Chromosomes (YAC) were used to clone large fragments of DNA for sequencing.
Question 575 of 668
📘 CLASS XII
Repetitive DNA that shows a high degree of polymorphism is the basis of?
DNA fingerprinting relies on the polymorphism found in repetitive DNA sequences (Satellite DNA), such as VNTRs.
Question 576 of 668
📘 CLASS XII
Which technique is used to separate DNA fragments based on size?
Gel electrophoresis separates DNA fragments according to their size, with smaller fragments moving faster through the gel.
Question 577 of 668
📘 CLASS XII
In DNA fingerprinting, the probe hybridizes with?
Radioactive probes are designed to hybridize with specific complementary VNTR sequences on the membrane.
Question 578 of 668
📘 CLASS XII
The technique of transferring DNA fragments from gel to a membrane is called?
Southern blotting is the transfer of DNA to a membrane (like nitrocellulose) for hybridization. Northern is for RNA, Western for protein.
Question 579 of 668
📘 CLASS XII
Polymorphism in DNA sequence is defined as a variation found in a population at a frequency of?
If an inheritable mutation is observed in a population at a frequency greater than 0.01 (1%), it is referred to as DNA polymorphism.
Question 580 of 668
📘 CLASS XII
Which scientist developed the technique of DNA Fingerprinting?
Sir Alec Jeffreys developed the technique of DNA fingerprinting using satellite DNA probes.
