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Molecular Basis of Inheritance MCQs

Class XII Biology NCERT Based NEET Practice

📘 Concept Based 📝 Exam Level 🤖 AI Explanations
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668 questions in this chapter
Question 221 of 668
📘 CLASS XII
Which bond is broken by the enzyme Helicase?
Helicase separates the two DNA strands by breaking the hydrogen bonds holding the nitrogenous bases together.
Question 222 of 668
📘 CLASS XII
The leading strand is synthesized in which direction?
The leading strand is synthesized continuously in the 5-prime to 3-prime direction, moving towards the replication fork.
Question 223 of 668
📘 CLASS XII
Which mutation results in the change of a single base pair?
A point mutation involves the substitution of a single base pair, as seen in Sickle Cell Anemia.
Question 224 of 668
📘 CLASS XII
Frameshift mutations are caused by?
Insertions or deletions of nucleotides (not in multiples of 3) shift the reading frame of the genetic code.
Question 225 of 668
📘 CLASS XII
The initiator tRNA in prokaryotes carries which amino acid?
In prokaryotes, the initiator tRNA is charged with N-formylmethionine (fMet). In eukaryotes, it is Methionine.
Question 226 of 668
📘 CLASS XII
Which site on the ribosome accepts the new incoming aminoacyl-tRNA?
The A-site (Aminoacyl site) is where the new tRNA carrying an amino acid enters the ribosome.
Question 227 of 668
📘 CLASS XII
During translation, the polypeptide chain is held at which site?
The P-site (Peptidyl site) holds the tRNA carrying the growing polypeptide chain.
Question 228 of 668
📘 CLASS XII
Termination of translation occurs when the ribosome encounters?
When a stop codon (UAA, UAG, UGA) reaches the A-site, no tRNA binds; instead, Release Factors bind to terminate translation.
Question 229 of 668
📘 CLASS XII
Which scientist proved that DNA replication is semi-conservative using Nitrogen isotopes?
Meselson and Stahl used N-15 and N-14 isotopes to prove the semi-conservative mode of replication.
Question 230 of 668
📘 CLASS XII
What is the function of the enzyme Permease in the Lac Operon?
Permease facilitates the entry of lactose into the bacterial cell.