Who proposed the triplet nature of the genetic code?
Physicist George Gamow proposed that since there are 4 bases and 20 amino acids, the code must consist of combinations of at least 3 bases (4^3=64) to cover all amino acids.
Question 192 of 668
📘 CLASS XII
Har Gobind Khorana is known for?
Khorana chemically synthesized defined RNA sequences (homopolymers like UUUUU... and copolymers) to help crack the genetic code.
Question 193 of 668
📘 CLASS XII
tRNA is also known as?
tRNA was formerly referred to as soluble RNA (sRNA) because it remains soluble in 1M NaCl solution.
Question 194 of 668
📘 CLASS XII
The 2D structure of tRNA resembles a?
The secondary (2D) structure of tRNA is depicted as a clover-leaf shape.
Question 195 of 668
📘 CLASS XII
The 3D structure of tRNA looks like?
The actual tertiary (3D) structure of tRNA is compact and resembles an inverted letter L.
Question 196 of 668
📘 CLASS XII
Amino acids attach to which end of the tRNA?
The amino acid acceptor arm is located at the 3-prime end of the tRNA molecule, where the specific amino acid binds.
Question 197 of 668
📘 CLASS XII
The loop of tRNA that reads the mRNA codon is called?
The anticodon loop contains a triplet sequence complementary to the mRNA codon, allowing the tRNA to recognize the code.
Question 198 of 668
📘 CLASS XII
Which enzyme catalyzes the charging of tRNA (Aminoacylation)?
This enzyme attaches the correct amino acid to its corresponding tRNA using ATP, a process called charging or aminoacylation.
Question 199 of 668
📘 CLASS XII
The formation of a peptide bond during translation is catalyzed by?
The ribosome itself (specifically the large rRNA component) acts as the enzyme peptidyl transferase to form peptide bonds between amino acids.
Question 200 of 668
📘 CLASS XII
In prokaryotes, the ribosome binding site on mRNA is called?
The Shine-Dalgarno sequence is a specific purine-rich sequence upstream of the start codon in prokaryotic mRNA that the small ribosomal subunit recognizes.
