Consider the following statements:
(A) Coenzyme or metal ion that is tightly bound to
enzyme protein is called prosthetic group.
(B) A complete catalytic active enzyme with its
bound prosthetic group is called apoenzyme.
Select the correct option.
Inhibition of Succinic dehydrogenase enzyme by
malonate is a classical example of:
AI-generated explanation. Check against your textbook.
Explanation:
Malonate inhibits succinic dehydrogenase by competing with succinate for the enzyme’s active site, making it a competitive inhibitor. This prevents normal substrate binding and slows the reaction in the citric acid cycle (succinate to fumarate). In NCERT terms, the inhibition occurs at the active site and is overcome by high substrate concentration, which is characteristic of competitive inhibition.
🧠 Did You Know?
Competitive inhibitors resemble the normal substrate and can be outcompeted by increasing substrate concentration.
💡 NCERT Memory Line:
Inhibition that resembles the substrate and competes for the active site = competitive inhibition.
Regarding catalytic cycle of an enzyme action,
selecte the correct sequential steps:
A. Substrate enzyme complex formation.
B. Free enzyme ready to bind with another
substrate.
C. Release fo products.
D. Chemical bonds of the substrate broken.
E. Substrate bindig to active site.
Choose the correct answer from the options given below: