The Central Dogma of molecular biology was proposed by _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• Watson
• Crick
• Wilkins
• Franklin
Correct Option: B  [ Crick ]

Remark: Francis Crick proposed the Central Dogma.

In some viruses, the flow of information is in reverse direction, which is called _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• Transcription
• Translation
• Reverse transcription
• Replication
Correct Option: C  [ Reverse transcription ]

Remark: Retroviruses show reverse transcription (RNA to DNA).

The length of DNA in a typical mammalian cell is approximately _______ meters.

[Molecular-Basis-of-Inheritance] [class-xii ]

• 1.1
• 2.2
• 3.3
• 4.4
Correct Option: B  [ 2.2 ]

Remark: The total length of double-stranded DNA in a human diploid cell is about 2.2 meters.

In prokaryotes, DNA is held with some positively charged proteins in a region called _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• Nucleus
• Nucleolus
• Nucleoid
• Cytoplasm
Correct Option: C  [ Nucleoid ]

Remark: The region containing DNA in prokaryotes is called the nucleoid.

In eukaryotes, there is a set of positively charged, basic proteins called _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• Polyamines
• Histones
• Protamines
• Albumins
Correct Option: B  [ Histones ]

Remark: Histones are the basic proteins responsible for DNA packaging in eukaryotes.

Histones are rich in the basic amino acid residues _______ and Arginine.

[Molecular-Basis-of-Inheritance] [class-xii ]

• Lysine
• Valine
• Leucine
• Histidine
Correct Option: A  [ Lysine ]

Remark: Histones are rich in Lysine and Arginine.

Histones are organized to form a unit of eight molecules called a histone _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• Tetramer
• Hexamer
• Octamer
• Dimer
Correct Option: C  [ Octamer ]

Remark: The core of the nucleosome is a histone octamer.

The negatively charged DNA is wrapped around the positively charged histone octamer to form a structure called _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• Chromosome
• Chromatin
• Nucleosome
• Nucleotide
Correct Option: C  [ Nucleosome ]

Remark: The nucleosome is the fundamental unit of chromatin packaging.

A typical nucleosome contains _______ bp of DNA helix.

[Molecular-Basis-of-Inheritance] [class-xii ]

• 100
• 200
• 300
• 400
Correct Option: B  [ 200 ]

Remark: A nucleosome typically contains about 200 base pairs of DNA.

Nucleosomes constitute the repeating unit of a structure in nucleus called _______

[Molecular-Basis-of-Inheritance] [class-xii ]

• Chromosome
• Chromatin
• Centromere
• Telomere
Correct Option: B  [ Chromatin ]

Remark: Chromatin is the thread-like structure composed of repeating nucleosomes.