Which environmental factors in tissues favor dissociation of oxygen from oxyhaemoglobin?
I. Low pO2 II. High pCO2 III. High H+ concentration IV. Higher temperature
Explanation: All four tissue conditions, namely low pO2, high pCO2, high H+ concentration, and higher temperature, promote the release of oxygen from oxyhaemoglobin.
Question 82 of 100
📘 CLASS XI
Under normal physiological conditions, how much oxygen is delivered to tissues by 100 mL of oxygenated blood?
I. Around 5 mL of O2. II. Around 4 mL of O2. III. Around 15 mL of O2. IV. Around 20 mL of O2.
Explanation: Statement I is correct. Every 100 mL of oxygenated blood delivers approximately 5 mL of oxygen to tissues under normal physiological conditions.
Question 83 of 100
📘 CLASS XI
Consider the transport modes of carbon dioxide in human blood:
I. 20-25 per cent is carried by haemoglobin as carbamino-haemoglobin. II. About 70 per cent is carried as bicarbonate (HCO3-). III. About 7 per cent is carried in dissolved state through plasma. IV. 97 per cent is carried bound to red blood cell iron centres.
Explanation: Statements I, II, and III are correct. Carbon dioxide is transported mainly as bicarbonate, partly as carbamino-haemoglobin, and a small amount in dissolved form. Statement IV is incorrect.
Question 84 of 100
📘 CLASS XI
Analyze the binding of carbon dioxide to haemoglobin:
I. CO2 binds to haemoglobin as carbamino-haemoglobin. II. Binding is related to partial pressure of CO2 (pCO2). III. pO2 is a major factor affecting this binding. IV. High pCO2 and low pO2 in tissues favor more CO2 binding.
Explanation: All four statements are correct. Carbon dioxide binds to haemoglobin as carbamino-haemoglobin. Its binding depends mainly on pCO2 and is also influenced by pO2; high pCO2 and low pO2 in tissues promote this binding.
Question 85 of 100
📘 CLASS XI
Consider the enzyme Carbonic Anhydrase:
I. RBCs contain a very high concentration of carbonic anhydrase. II. Minute quantities of carbonic anhydrase are present in plasma. III. Facilitates the reversible reaction: CO2 + H2O ⇌ H2CO3 ⇌ HCO3- + H+. IV. Absent in RBCs and found exclusively in gastric mucosal glands.
Explanation: Statements I, II, and III are correct. Carbonic anhydrase is abundant in RBCs, present in small amounts in plasma, and catalyzes the reversible hydration of carbon dioxide. Statement IV is incorrect.
Question 86 of 100
📘 CLASS XI
Examine the direction of carbonic anhydrase reaction at tissue vs alveolar sites:
I. At tissue site (high pCO2), CO2 diffuses into blood and forms HCO3- and H+. II. At alveolar site (low pCO2), reaction proceeds in opposite direction forming CO2 and H2O. III. CO2 trapped as bicarbonate at tissues is released out as CO2 at alveoli. IV. Reaction proceeds unidirectionally at all body sites regardless of pCO2.
Explanation: Statements I, II, and III are correct. High tissue pCO2 drives bicarbonate formation, whereas low alveolar pCO2 reverses the reaction to produce CO2 gas for expiration. Statement IV is incorrect because the reaction is reversible and governed by pCO2.
Question 87 of 100
📘 CLASS XI
Under normal physiological conditions, how much carbon dioxide is delivered to alveoli by 100 mL of deoxygenated blood?
I. Approximately 4 mL of CO2. II. Approximately 5 mL of CO2. III. Approximately 15 mL of CO2. IV. Approximately 20 mL of CO2.
Explanation: Statement I is correct. Every 100 mL of deoxygenated blood delivers approximately 4 mL of CO2 to the alveoli.
Question 88 of 100
📘 CLASS XI
Consider the Respiratory Rhythm Centre:
I. Located in the medulla region of the brain. II. Primarily responsible for regulation of respiratory rhythm. III. Located in the cerebellum. IV. Located in the spinal cord dorsal horn.
Explanation: Statements I and II are correct. A specialized center in the medulla region called the respiratory rhythm center is primarily responsible for regulating respiratory rhythm. Statements III and IV are incorrect location claims.
Question 89 of 100
📘 CLASS XI
Analyze the Pneumotaxic Centre in the human brain:
I. Located in the pons region of the brain. II. Can moderate the functions of the respiratory rhythm centre. III. Neural signals from this centre can reduce the duration of inspiration. IV. Can alter the respiratory rate.
Explanation: All four statements are correct. The pneumotaxic center in the pons moderates the respiratory rhythm center, reducing inspiration duration and thereby altering respiratory rate.
Question 90 of 100
📘 CLASS XI
Regarding the Chemosensitive Area in the brain, consider the statements:
I. Situated adjacent to the rhythm centre. II. Highly sensitive to CO2 and hydrogen ions (H+). III. Activation of this centre signals rhythm centre to make necessary adjustments to eliminate CO2 and H+. IV. Highly sensitive to changes in nitrogen gas concentrations.
Explanation: Statements I, II, and III are correct. The chemosensitive area adjacent to the rhythm center senses increased CO2 and H+ to signal the rhythm center for necessary respiratory adjustments. Statement IV is incorrect because it responds to CO2 and H+, not nitrogen.